A clinicopathological study of cutaneous lichen planus
نویسندگان
چکیده
منابع مشابه
Foxp3 gene expression in oral lichen planus: a clinicopathological study.
CD4+CD25+ Forkhead‑box protein 3 (Foxp3+) regulatory T cells are important in oral lichen planus (OLP). The present study aimed to investigate Foxp3 expression in CD4+CD25+ T cells of peripheral blood mononuclear cells and oral lesions in patients diagnosed with OLP, who were grouped as OLP subtype, duration and relapse. Using quantitative polymerase chain reaction (qPCR), western blotting and ...
متن کاملLichen Sclerosus et Atrophicus with Cutaneous Distribution Simulating Lichen Planus
Lichen sclerosus (LS) et atrophicus is a disease of unknown etiology, although hereditary, endocrine, and autoimmune factors are known to be involved. While the anal and genital regions are predominantly affected, only 2.5% of patients present with extragenital lesions, particularly of the trunk, neck, and upper limbs. The possible relationship between lichen sclerosus et atrophicus and both li...
متن کاملQualitative and quantitative study of immune cells in various types of cutaneous lichen planus
Background: Lichen planus (LP) is a common inflammatory skin disease. Pathogenesis of LP includes two possible mechanisms; related or unrelated to antigen. Regarding different clinical features of cutaneous and mucosal types of LP, for the first time, we decided to perform a qualitative and quantitative study of immune cells in different types of cutaneous LP and in comparison with normal skin....
متن کاملImmunohistochemical study of lichen planus.
The distribution of IgM and IgG in 20 cases of lichen planus and five cases of non-specific inflammation were studied by the unlabelled antibody-enzyme (PAP) technique. Routine paraffin sections were used. In lichen planus deposits of immunoglobulins were seen in and around epithelial cells, in colloid bodies, at epidermo-dermal junctions, and in some inflammatory cells. All cases examined for ...
متن کاملA retrospective clinicopathological study on oral lichen planus and malignant transformation: Analysis of 518 cases
OBJECTIVE To investigate the epidemiological and clinical characteristics of a relatively large cohort of patients with oral lichen planus (OLP) from eastern China. STUDY DESIGN A total of 518 patients with histologically confirmed OLP in a long-term follow-up period (6 months-21.5 years) were retrospectively reviewed in our clinic. RESULTS Of the 518 patients, 353 females and 165 males wer...
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ژورنال
عنوان ژورنال: Journal of Dermatology & Dermatologic Surgery
سال: 2015
ISSN: 2352-2410
DOI: 10.1016/j.jssdds.2013.12.003